Study this topic, specifically for your vSphere version and SQL Server Editions and configure everything accordingly. Note that SQL Server Enterprise Edition is required to really benefit from NUMA topology. NUMA and vNUMA architecture is strongly recommended for SQL Server environments, as SQL Server is NUMA-aware.Set Power Option to “High Performance” on host and VM Operating Systems.Disable any unused devices (for example, serial ports).Select the appropriate snoop mode to allow the processor to check the cache contents of both local and remote processors for data.Disable all processor C-states (including the C1E halt state).Set power management (or its vendor-specific equivalent label) to “OS controlled.”.Verify that all ESXi hosts have NUMA (Non-Uniform Memory Access) enabled in the system BIOS.Enable Turbo Boost and Hyper-Threading (HT) on the BIOS.Ensure latest versions of BIOS and Firmware are in place.Here are the main best practices VMware recommends, and the most important based on Pythian’s experience (SQL Server on Windows): BIOS (basic input / output system): In case the link doesn’t work for you, or you have a different version of VMware, you can search for the proper SQL Server best practices on the VMware site. VMware has created a very detailed best-practice document for us, specifically for SQL Server. At the same time, to avoid performance decreases, it’s vital to make sure that different VMs are not competing with each other on resources in a way that may starve one of them. Now you need to create virtual machines on it and ensure each machine gets the proper amount of resources. Imagine you have a host server with specific specs. Did you know it’s very important to ensure that your VMware environment is properly set when hosting SQL Server instances?
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